In a large bowl mix together the ground beef, pork and breadcrumbs until fully combined.
In a medium-sized bowl, whisk the eggs together with the milk, 1 1/4 teaspoon salt, Italian seasoning, pepper, garlic powder, and onion powder.
Stir the whisked egg mixture, and 3 tablespoons ketchup into the meat, until fully combined. Use a stand mixer for this step if you have one.
In a small bowl mix together the remaining 1 tablespoon ketchup, brown sugar, Worcestershire sauce and water until fully combined.
Place the broccoli and potatoes on the baking sheet and drizzle with olive oil and remaining 3/4 teaspoon salt. Toss to coat evenly and spread it all out on the baking sheet. Divide the meat into 6 pieces and create an oval about 4” by 3”. Nestle them between the broccoli and potatoes.
Using a pastry brush, brush the brown sugar sauce over the tops of the meatloaves.
Bake in the oven for 30 minutes until the internal temperature of the meatloaf registers 160°F with an instant read thermometer.